Topical cell-free conditioned media harvested from adipose tissue-derived stem cells promote recovery from corneal epithelial defects caused by chemical burns.
RatBurnChemical / corrosiveSprague-DawleyMalen = 10 rats per group across 4 groupsTopical eye dropsConditioned medium concentrated 60-fold then diluted to 30-…First dose immediately after epithelial removal
Model: Corneal chemical burn from 100 per cent alcohol-soaked filter paper applied for 50 seconds
Topical conditioned medium accelerated corneal re-epithelialisation, raised HGF and EGF expression and lowered inflammatory cytokines compared with untreated burn controls.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.