PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2020

EVALUATION OF THE EFFECT OF ADEMOL ON THE DYNAMICS OF NEURON-SPECIFIC ENOLASE IN TRAUMATIC BRAIN INJURY IN RATS.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 32672703 ↗2020Reported benefit

EVALUATION OF THE EFFECT OF ADEMOL ON THE DYNAMICS OF NEURON-SPECIFIC ENOLASE IN TRAUMATIC BRAIN INJURY IN RATS.

RatTBIUnspecifiedIntravenous2 mg/kg

Model: Acute experimental traumatic brain injury (model of head injury; induction method not described in the abstract)

Over 8 days, ademol 2 mg/kg and amantadine sulfate 5 mg/kg reduced the rise in neuron-specific enolase relative to the control pathology group by an average of 52.1% and 38.2% respectively; ademol exceeded the reference drug by an average of 22.5%.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.