Mesenchymal stem cells derived-exosomes as a new therapeutic strategy for acute soft tissue injury.
RatCrushOther / unspecifiedSprague-DawleyMalen = 24 rats in 4 groups (n = 6 per group)
Model: Acute soft tissue injury induced by a strike (contusion) model
Exosomes of approximately 100 nm were isolated from rat bone marrow mesenchymal stem cells and characterised by nanoparticle tracking, electron microscopy and Western blot. Severe soft tissue inflammation in the strike group was alleviated by both stem cell and exosome treatment. Exosome treatment…
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