Combination of curcumin with autologous transplantation of adult neural stem/progenitor cells leads to more efficient repair of damaged cerebral tissue of rat.
RatTBIUnspecifiedWistarMalen = 36 male Wistar rats randomised into six groupsCurcumin in DMSO, route not stated; cells and PuraMatrix transplanted into the lesion siteCurcumin 100 mg/kg in DMSO; one group received curcumin 1 m…Following acute brain injury
Model: Stereotactic acute cerebral injury following stereotactic biopsy of subventricular zone tissue
Combination of neural stem/progenitor cells with PuraMatrix and curcumin reduced lesion size, astrogliosis, macrophage and microglial reaction and apoptotic cell number, with graft survival and differentiation at 4 weeks and improved neurological status.
Extraction: extract · Supplied extraction confidence: 0.72. Machine-extracted fields require source verification.