An injectable liposome for sustained release of icariin to the treatment of acute blunt muscle injury.
RatCrushLimb / muscle crushSprague-DawleyMaleInjection (liposome prepared by thin-film dispersion method)After muscle injury
Model: Acute blunt skeletal muscle injury
Icariin liposome promoted MHCIIB, vimentin and desmin expression, reduced collagen I, lowered TNF-alpha and IL-6, reduced malondialdehyde and increased superoxide dismutase activity, indicating improved muscle repair.
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.