Bacterial adhesion inhibitor prevents infection in a rodent surgical incision model.
RatWoundSprague-DawleyMaleTopical application to the incision siteAt the time of infection of the incision
Model: Surgical incision infected with antibiotic-resistant bioluminescent Gram-positive and Gram-negative bacterial strains
MAM7 inhibitor treatment reduced bacterial burden below the detection threshold, with significantly higher bacterial loads in control-treated groups, indicating reduced colonisation by clinically relevant pathogens in a surgical infection model.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.