Effect of Combining Low Temperature Plasma, Negative Pressure Wound Therapy, and Bone Marrow Mesenchymal Stem Cells on an Acute Skin Wound Healing Mouse Model.
MouseWoundICRLow temperature plasma applied topically to the wound surface; negative pressure wound therapy applied topically by sealed foam dressing and vacuum pump; mesenchymal stem cells injected subcutaneously into the wound edgeLow temperature plasma 3 min per day at 3 cm distance (5.99…Treatment started after wounding and was given daily from day 0
Model: Acute full-thickness dorsal excisional skin wound created with a 12 mm dermal biopsy punch under isoflurane anaesthesia
Wound area remaining at day 7 was 53.4 per cent in untreated controls versus 26.8 per cent with low temperature plasma, 24.5 per cent with mesenchymal stem cells and 24.8 per cent with negative pressure wound therapy, falling further with combinations to 16.9, 15.5 and 15.7 per cent for the paired…
Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.