Methanolic extract of Ephedra ciliata promotes wound healing and arrests inflammatory cascade in vivo through downregulation of TNF-alpha.
RatWoundMale and femaleTopical (wound models); systemic (anti-inflammatory models)20% cream topically for wound models; 200 mg/kg for anti-in…After wounding
Model: Excision and burn skin wounds, with carrageenan paw oedema and cotton pellet granuloma inflammation models
The quercetin-rich extract promoted dose and time-dependent wound closure comparable with heparin, inhibited granuloma formation, improved skin histological architecture, downregulated serum TNF-alpha and showed no adverse effect on vascular development.
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.