Evaluation of ROCEN on Burn Wound Healing and Thermal Pain: Transforming Growth Factor-beta1 Activation.
RatBurnUnspecifiedTopicalTopical formulation containing 2 per cent arthrocen
Model: Second-degree thermal burn wound in rats
ROCEN significantly improved burn wound healing parameters by 7 days and reduced wound surface area over 14 days relative to control, with TGF-beta1 elevation comparable to zinc oxide cream. It also produced significant analgesia on tail-flick and hot plate testing.
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