TMT-based proteomics analysis reveals the protective effects of Xuefu Zhuyu decoction in a rat model of traumatic brain injury.
RatTBIControlled cortical impactSprague-DawleyMaleOral gavage9 g/kg/day
Model: Controlled cortical impact traumatic brain injury
Xuefu Zhuyu decoction improved neurological function, reduced brain oedema and improved cell morphology around the injured area in controlled cortical impact rats. Of 105 overlapping differentially expressed proteins, 17 were regulated by treatment and mapped predominantly to platelet activation an…
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