PRECLINICAL PUBLICATION · 2015

Wound healing properties of hyaluronan derivatives bearing ferulate residues.

Mouse / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Hyaluronan-ferulate graft copolymer HAFA-17 (grafting degree 7%)

PMID 32262706 ↗2015Reported benefit

Wound healing properties of hyaluronan derivatives bearing ferulate residues.

MouseWoundSKH1

Model: In vitro scratch wound in human HaCaT keratinocytes and in vivo cutaneous wound in SKH1 mice

HAFA-17 significantly improved in vitro scratch wound closure relative to hyaluronic acid and ferulic acid controls, increased keratinocyte proliferation by BrdU assay, and improved wound closure rate in SKH1 mice in vivo.

Extraction: extract · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.