An improvement in acute wound healing in rats by the synergistic effect of photobiomodulation and arginine.
RatWoundWistarMalen = 6 per group, 4 groups per phase, 24 rats per phase, 48 rats…Topical ointment; intraperitoneal injection for the arginine injection arm; transcutaneous laserArginine ointment 2 percent or 5 percent, approximately 0.0…Photobiomodulation started immediately after surgery; arginine started after wo…
Model: Single 15 mm full-thickness round excisional skin wound including the skin muscle on the proximal back, under ketamine 50 mg/kg and xylazine 5 mg/kg intramuscular anaesthesia
Arginine 2 percent was the most effective single arginine regimen for wound area reduction (p=0.000 versus arginine 5 percent, arginine injection and control). Photobiomodulation alone and photobiomodulation plus arginine 2 percent significantly improved wound strength and nearly all stereological…
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