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PRECLINICAL PUBLICATION · 2020

Terminalia catappa L. infusion accelerates the healing process of gastric ischemia-reperfusion injury in rats.

Rat / Ischaemia-reperfusion

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 32240780 ↗2020Reported benefit

Terminalia catappa L. infusion accelerates the healing process of gastric ischemia-reperfusion injury in rats.

RatIschaemia-reperfusionOther / unspecifiedSprague-DawleyMaleOral30, 100 and 300 mg/kgAcute pretreatment before ischaemia-reperfusion and subacute treatment for 3 da…

Model: Gastric ischaemia and reperfusion induced gastric lesion

Pretreatment at 100 mg/kg reduced myeloperoxidase activity by 38 percent without a clear macroscopic effect on lesion area. Three days of treatment at 30 and 100 mg/kg reduced lesion area by 95 percent and 89 percent respectively (p<0.05), with myeloperoxidase reduced by 70 to 78 percent and matrix…

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.