Gastrointestinal vascular permeability changes following spinal cord injury.
MouseSpinal cord injuryContusionC57BL/6MaleIntravenousFollowing injury; imaging at 48 hours, 2 weeks and 4 weeks
Model: Contusion spinal cord injury
A single dose reduced vascular permeability at 48 hours but only transiently. Multiple administrations significantly decreased gastrointestinal vascular permeability at 4 weeks, improved sustained agonist-induced intestinal contraction and reduced ileal sICAM-1 compared with saline.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.