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PRECLINICAL PUBLICATION · 2020

Tartary buckwheat extract alleviates alcohol-induced acute and chronic liver injuries through the inhibition of oxidative stress and mitochondrial cell death pathway.

Rat / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 32051738 ↗2020Reported benefit

Tartary buckwheat extract alleviates alcohol-induced acute and chronic liver injuries through the inhibition of oxidative stress and mitochondrial cell death pathway.

RatChemical/toxinMedium dose 16.70 mL/kg body weight

Model: Alcohol-induced acute and chronic liver injury in alcohol-exposed rats; alcohol-exposed primary cultured hepatocytes, HepG2 and Huh7 cells in vitro

Tartary buckwheat extract, similar to curcumin, reduced elevated serum aspartate aminotransferase and alanine aminotransferase, improved liver index, lowered hepatic malondialdehyde and restored hepatic glutathione in both acute and chronic alcohol-induced liver injury. A medium dose alleviated hep…

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.