Effects of electroacupuncture on functional indices and pS6 expression following acute sciatic nerve crush injury in rats.
RatCrushPeripheral-nerve crushSprague-DawleyMalen = 108 rats allocated overall (28 for sciatic functional index…Percutaneous electroacupuncture at acupoints GB30 and ST36Commenced after crush injury, with assessment at 7, 14, 28 and 42 days post-ope…
Model: Acute sciatic nerve crush injury created by mechanical clamping of the sciatic nerve stem
Electroacupuncture significantly promoted recovery of the injured sciatic nerve as measured by the sciatic functional index and increased pS6 expression at the crush site. Local rapamycin injection reduced pS6 expression and hindered the therapeutic effect of electroacupuncture, and pS6 level corre…
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