Protective effect of diallyl disulfide against cerulein-induced acute pancreatitis and associated lung injury in mice.
MouseChemical/toxinMale
Model: Cerulein-induced acute pancreatitis with associated lung injury
Diallyl disulfide attenuated the severity of pancreatic and pulmonary inflammation, lowering serum amylase and myeloperoxidase activity and improving histology. The effect was associated with reduced TNF-alpha, cystathionine-gamma-lyase, preprotachykinin A and NK1R expression, lower hydrogen sulfid…
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