PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2020

Implantation of a functional TEMPO-hydrogel induces recovery from rat spinal cord transection through promoting nerve regeneration and protecting bladder tissue.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 31989134 ↗2020Reported benefit

Implantation of a functional TEMPO-hydrogel induces recovery from rat spinal cord transection through promoting nerve regeneration and protecting bladder tissue.

RatSpinal cord injuryComplete transectionMaleImplantation into the spinal cord lesionAcute, at the time of transection

Model: Complete spinal cord transection

Implantation of the TEMPO-functionalised hydrogel produced significant restoration of motor function, promoted nerve fibre regeneration and bridging of the lesion, and protected bladder tissue from neurogenic damage.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.