Vincetoxicum arnottianum ameliorate inflammation by suppressing oxidative stress and pro-inflammatory mediators in rat.
RatChemical/toxinSprague-DawleyMale300 mg/kg for the ethyl acetate fraction
Model: Carrageenan, formalin and Freund's complete adjuvant-induced paw oedema and croton oil-induced ear inflammation
The ethyl acetate fraction at 300 mg/kg gave the strongest anti-inflammatory activity, inhibiting oedema by 78.06 +/- 4.6 per cent (carrageenan), 54.71 +/- 0.34 per cent (formalin) and 73.12 +/- 1.9 per cent (croton oil), and restoring raised serum IL-1beta, TNF-alpha, IL-6, IL-17 and nitric oxide…
Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.