PRECLINICAL PUBLICATION · 2020

Neural stem cell-derived exosomes facilitate spinal cord functional recovery after injury by promoting angiogenesis.

Mouse / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Neural stem cell-derived exosomes (NSCs-Exos)

PMID 31903774 ↗2020Reported benefit

Neural stem cell-derived exosomes facilitate spinal cord functional recovery after injury by promoting angiogenesis.

MouseSpinal cord injuryUnspecifiedC57BL/6Female

Model: Acute traumatic spinal cord injury in mice

Neural stem cell-derived exosomes increased microvascular density, reduced spinal cord cavity size and improved Basso mouse scale scores, with effects partially abolished by VEGF-A knockdown.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.