Acute postburn edema: role of strongly negative interstitial fluid pressure.
RatBurnUnspecifiedInbred strain not specifiedFemaleIntravenousDuring acute postburn oedema formation
Model: Thermal skin injury to 10% or 40% of total body surface area, studied in vivo and post mortem
Interstitial fluid pressure fell from about -1 mmHg to -20 mmHg after 10% burns and -31 mmHg after 40% burns. Intravenous fluid infusion rapidly returned pressure to slightly positive values. When fluid transfer was restricted (post-mortem injury, or a subcutaneous barrier) pressure fell to -95 and…
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