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PRECLINICAL PUBLICATION · 2020

Malabaricone C Attenuates Nonsteroidal Anti-Inflammatory Drug-Induced Gastric Ulceration by Decreasing Oxidative/Nitrative Stress and Inflammation and Promoting Angiogenic Autohealing.

Mouse / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 31830804 ↗2020Reported benefit

Malabaricone C Attenuates Nonsteroidal Anti-Inflammatory Drug-Induced Gastric Ulceration by Decreasing Oxidative/Nitrative Stress and Inflammation and Promoting Angiogenic Autohealing.

MouseChemical/toxinmale (per MeSH)

Model: NSAID induced gastric ulceration in mice (indomethacin indexed in MeSH)

Malabaricone C dose dependently reduced NSAID induced gastric erosion and inflammation and improved survival, performing as well as or better than omeprazole without blunting NSAID anti-inflammatory efficacy.

Extraction: extract · Supplied extraction confidence: 0.45. Machine-extracted fields require source verification.