Gingko Biloba protects cardiomyocytes against acute doxorubicin induced cardiotoxicity by suppressing oxidative stress.
RatChemical/toxinReported as "Wistar Sprague"; MeSH indexing lists Rats, WistarMalen = 30 rats in total, 10 per group across three groupsCo-administered with doxorubicin
Model: Acute doxorubicin induced cardiotoxicity, doxorubicin 20 mg/kg
Doxorubicin raised cardiac troponin I, brain natriuretic peptide, caspase-3, lipid peroxidase, malondialdehyde and tumour necrosis factor alpha and lowered glutathione compared with controls (p<0.01). Co-administration of Ginkgo biloba significantly reduced cardiac troponin I and caspase-3 and rais…
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