A polysaccharide fraction from "ipe-roxo" (Handroanthus heptaphyllus) leaves with gastroprotective activity.
RatChemical/toxinWistarFemaleOral and intraperitoneal
Model: Ethanol-induced acute gastric lesion, indomethacin-induced gastric ulcer, and a gastric ulcer healing model; parallel oxidative stress model in Caco-2 human epithelial cells
Oral and intraperitoneal HHSF protected the gastric mucosa in the ethanol model and preserved gastric mucus. In the indomethacin model HHSF reduced wounded area and prevented mucus and glutathione depletion, and it accelerated gastric ulcer healing while maintaining glutathione levels. HHSF preserv…
Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.