PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2019

Recombinant annexin A6 promotes membrane repair and protects against muscle injury.

Mouse / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 31545299 ↗2019Reported benefit

Recombinant annexin A6 promotes membrane repair and protects against muscle injury.

MouseOther

Model: Acute skeletal muscle plasma membrane injury in vitro and in vivo, plus a mouse model of muscular dystrophy

Recombinant annexin A6 reduced membrane injury and protected against acute muscle injury in vitro and in vivo, and lowered serum creatine kinase in a muscular dystrophy model, consistent with enhanced membrane repair.

Extraction: extract · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.