Hybrid material for open abdomen: saving the wound from intestinal fistula.
RatWoundSprague-Dawleymaletopical application of patch to the wound
Model: Open abdomen wound with intestinal fistula
The hybrid patch allowed cells to survive in the presence of bacteria and accelerated wound healing in the open abdomen and intestinal fistula model, with no additional organ damage on sub-acute toxicity scoring.
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