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PRECLINICAL PUBLICATION · 2019

P1G10, the Proteolytic Fraction from, Stimulates Tissue Repair after Acute Exposure to Ultraviolet B Radiation.

Mouse / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 31489890 ↗2019Reported benefit

P1G10, the Proteolytic Fraction from, Stimulates Tissue Repair after Acute Exposure to Ultraviolet B Radiation.

MouseRadiationHRS/J hairlessMalen = 5 animals per group, five groupsTopicalAfter ultraviolet B exposure

Model: Single acute ultraviolet B skin exposure at 2.4 J/cm2

Topical P1G10 reduced erythema, increased hypodermal cellularity, reversed ultraviolet B induced depletion of antioxidant defences, lowered malondialdehyde, and inhibited MMP-9 and caspase-3 while increasing p53.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.