CCL5 deficiency promotes liver repair by improving inflammation resolution and liver regeneration through M2 macrophage polarization.

CCL5 deficiency promotes liver repair by improving inflammation resolution and liver regeneration through M2 macrophage polarization.

Model: Acetaminophen-induced acute liver injury

CCL5 deficiency did not alter the early phase but promoted late-phase liver repair through inflammation resolution and regeneration with more hepatic M2 macrophages; CCL5 blockade with a neutralising antibody or Met-CCL5 alleviated liver injury and improved survival.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.