Galantamine improves functional recovery and reduces lesion size in a rat model of spinal cord injury.
RatSpinal cord injuryContusionWistarMaleIntraperitoneal5 mg/kg
Model: Contusion spinal cord injury using the NYU/MASCIS impactor
Galantamine-treated rats had significantly higher BBB scores than lesion controls, a higher percentage of NFM-positive cells at 6 weeks post-injury and reduced lesion size, indicating increased tissue survival and faster hind limb motor recovery.
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