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PRECLINICAL PUBLICATION · 2018

Vitex agnus-castus safeguards the lung against lipopolysaccharide-induced toxicity in mice.

Mouse / Endotoxin/LPS

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 31353538 ↗2018Reported benefit

Vitex agnus-castus safeguards the lung against lipopolysaccharide-induced toxicity in mice.

MouseEndotoxin/LPSBALB/c

Model: Lipopolysaccharide-induced acute lung injury

Vitex agnus-castus extract reduced pulmonary oedema, bronchoalveolar lavage protein and lactate dehydrogenase, and inflammatory cell infiltration after LPS challenge, and reversed histopathological lung lesions. Lung malondialdehyde fell while superoxide dismutase activity and reduced glutathione r…

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.