5-hydroxymethylfurfural-embedded poly (vinyl alcohol)/sodium alginate hybrid hydrogels accelerate wound healing.
WoundTopical hydrogel dressing applied to the wound
Model: Cutaneous wound healing model in vivo, with in vitro studies in human skin fibroblasts
5-HMF promoted proliferation, migration and collagen production in human skin fibroblasts in vitro. The 5-HMF-loaded PVA/sodium alginate hydrogel gave sustained release and accelerated wound healing in vivo with reduced inflammation, greater angiogenesis, more collagen and improved re-epithelialisa…
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