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PRECLINICAL PUBLICATION · 2019

Dietary supplementation with Zyflamend poly-herbal extracts and fish oil inhibits intimal hyperplasia development following vascular intervention.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 31306903 ↗2019Reported benefit

Dietary supplementation with Zyflamend poly-herbal extracts and fish oil inhibits intimal hyperplasia development following vascular intervention.

RatOtherSprague-DawleyMaleDietary supplementationHuman equivalent doses of Zyflamend and Wholemega; exact am…Supplementation started 1 week before balloon angioplasty

Model: Balloon angioplasty-induced injury of the left carotid artery leading to intimal hyperplasia, assessed 28 days after injury

Combined Zyflamend and Wholemega supplementation reduced intimal hyperplasia at 28 days after balloon angioplasty compared with placebo, whereas either supplement alone had no significant effect. The combination lowered injury-induced serum interleukins, interferon-gamma and macrophage inflammatory…

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.