Human umbilical cord mesenchymal stem cells pretreated with Angiotensin-II attenuate pancreas injury of rats with severe acute pancreatitis.
RatOtherIntravenous injection via the tail vein12 hours after induction of severe acute pancreatitis
Model: Severe acute pancreatitis in rats; induction method not stated in the abstract
Angiotensin II-pretreated human umbilical cord mesenchymal stem cells significantly inhibited pancreatic injury, reducing pancreatitis severity scores and serum amylase and lipase compared with untreated cells. Conditioned medium from the pretreated cells reduced HUVEC apoptosis and increased tube…
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