Impact of different temperature stimuli on the expression of myosin heavy chain isoforms during recovery from bupivacaine-induced muscle injury in rats.
RatChemical/toxinWistarMaleLocal external thermal applicationIcing at 0 C for 20 min; intermittent heat stress at 42 C f…Icing immediately after injury; intermittent heat stress during days 2 to 14 af…
Model: Skeletal muscle injury induced by intramuscular injection of bupivacaine into the soleus muscle
Injury produced a transient increase in developmental, IId/x and IIb myosin heavy chain isoforms and hybrid fibres followed by recovery toward control values; icing partially delayed restoration of the myosin heavy chain profile, whereas repeated heat stress facilitated recovery of both the myosin…
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