Pectolinarigenin promotes functional recovery and inhibits apoptosis in rats following spinal cord injuries.
RatSpinal cord injuryContusionSprague-DawleyMalen = 36 rats in six groups of sixIntraperitoneal10, 30 and 50 mg/kgAfter injury
Model: Acute spinal cord injury by T10 laminectomy and a modified Allen method dropping a 10 g rod from 4 cm onto the dorsal cord surface
Pectolinarigenin improved locomotor scores dose dependently, increased surviving neurons, reduced TUNEL-positive cells and lowered apoptosis-related proteins, with 50 mg/kg comparable to methylprednisolone.
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.