PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2019

A short peptide potentially promotes the healing of skin wound.

Mouse / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 30842341 ↗2019Reported benefit

A short peptide potentially promotes the healing of skin wound.

MouseWoundmalen = Nine mice for the wound healing assay and a further nine fo…topical application to the wound0.1, 1 and 10 nM, 20 uL per woundfrom wounding to postoperative day 10

Model: Two full-thickness dorsal skin wounds, 8 x 8 mm

OA-GL12 accelerated wound closure in a time and concentration dependent manner, with healing rate at 10 nM reaching 95.03 +/- 1.90 percent by day 10, and showed no acute toxicity or haemolytic activity.

Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.