Overlay repair with a synthetic collagen scaffold improves the quality of healing in a rat rotator cuff repair model.
RatOtherSprague-Dawleyn = 40 animalsSurgical overlay augmentation at the repair siteAt the time of tendon repair
Model: Modified rat rotator cuff defect model with supraspinatus tendon detachment and repair
Scaffold augmentation improved the histological score at 12 weeks (8.4 of 15 versus 6.4 of 15, p = 0.032) and supported tendon-derived cell growth without provoking immunogenic responses, but did not produce a meaningful increase in biomechanical repair strength.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.