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PRECLINICAL PUBLICATION · 2019

Synthesis, characterization, antioxidant power and acute toxicity of some new azo-benzamide and azo-imidazolone derivatives with in vivo and in vitro antimicrobial evaluation.

Rat / Burn

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 30685693 ↗2019Reported benefit

Synthesis, characterization, antioxidant power and acute toxicity of some new azo-benzamide and azo-imidazolone derivatives with in vivo and in vitro antimicrobial evaluation.

RatBurnUnspecifiedWistarFemale

Model: Burn wound in rats infected with Staphylococcus aureus

Tested compounds showed high antimicrobial activity and improved wound healing compared with the ucederm control, with no lethality at a limit test dose of 2000 mg/kg and a maximum tolerated dose of 5000 mg/kg.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.