PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2018

Radioprotective effect of Hohenbuehelia serotina polysaccharides through mediation of ER apoptosis pathway in vivo.

Mouse / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 30605745 ↗2018Reported benefit

Radioprotective effect of Hohenbuehelia serotina polysaccharides through mediation of ER apoptosis pathway in vivo.

MouseRadiationMale

Model: Gamma-radiation-induced damage model

The polysaccharides reduced gamma-radiation-induced splenocyte apoptosis by blocking three endoplasmic reticulum apoptosis pathways and caspase-12 activation, with no acute or chronic toxicity in the tested range.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.