Tabebuia aurea decreases hyperalgesia and neuronal injury induced by snake venom.
MouseChemical/toxinSwissMaleOral180, 540, 720, 810 or 1080 mg/kg, with 720 mg/kg the effect…30 min before venom inoculation
Model: Intraplantar inoculation of Bothrops mattogrossensis venom, with a maximum hyperalgesic dose of 3 micrograms per paw
Oral extract at 720 mg/kg reduced venom-induced hyperalgesia without motor impairment and lowered inflammatory infiltrate and ATF-3 expression from 35.4% to 25.9%.
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.