Neuroectodermal stem cells: A remyelinating potential in acute compressed spinal cord injury in rat model.
RatSpinal cord injuryCompressionWistarIntralesional injection at the site of injury using a Hamilton syringe1 day after injury (acute) or 7 days after injury (subacute)
Model: Compressed spinal cord injury
Untreated injury produced haemorrhage, cavitation, reactive astrocytosis, upregulated GFAP, axoplasmic degeneration and demyelination. Grafting NESCs at 1 day after injury reduced the astrocyte reaction and pathological change, enhanced remyelination qualitatively and quantitatively, and improved l…
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