Mechanical Augmentation With Absorbable Alginate Sheet Enhances Healing of the Rotator Cuff.
RatOtherSprague-Dawley (wild-type)Malen = 40 rats randomised into 2 groupsImplanted locally at the supraspinatus tendon-to-bone repair siteAt the time of index rotator cuff repair surgery
Model: Surgically created supraspinatus tendon tear with acute tendon-to-bone repair
At 12 weeks the alginate-augmented group had a greater mean ultimate failure load (61.44 plus or minus 43.67 N versus 23.70 plus or minus 3.87 N, P = 0.023) and mean ultimate stress (7.36 plus or minus 2.87 MPa versus 2.83 plus or minus 0.50 MPa, P = 0.020), while 6-week biomechanical outcomes did…
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