Identification of Specific miRNAs in Neutrophils of Type 2 Diabetic Mice: Overexpression of miRNA Accelerates Diabetic Wound Healing.
MouseWoundMaleLocal application at the wound site
Model: Skin wound in type 2 diabetic mice
miRNA expression differed between diabetic and non-diabetic bone marrow neutrophils, and overexpression of the identified miRNA at the wound site of type 2 diabetic mice accelerated wound healing, implicating miRNA-regulated genes in neutrophil dysfunction and chronic inflammation in diabetic wound…
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