Apremilast ameliorates carfilzomib-induced pulmonary inflammation and vascular injuries.
RatChemical/toxinMale
Model: Carfilzomib-induced acute lung injury and pulmonary vascular injury
Apremilast reduced myeloperoxidase activity, tumour necrosis factor alpha levels and alveolar infiltrating cells and reversed the observed toxic effects of carfilzomib, preventing acute lung injury in rats.
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