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PRECLINICAL PUBLICATION · 2019

Beneficial Effects of Kaempferol after Developmental Traumatic Brain Injury Is through Protection of Mitochondrial Function, Oxidative Metabolism, and Neural Viability.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 30430900 ↗2019Reported benefit

Beneficial Effects of Kaempferol after Developmental Traumatic Brain Injury Is through Protection of Mitochondrial Function, Oxidative Metabolism, and Neural Viability.

RatTBIUnspecifiedSprague-DawleyMaleIntraperitoneal1 mg/kgFirst dose 1 h after injury

Model: Mild to moderate traumatic brain injury during early development; injury device, force and duration not stated

Kaempferol improved tricarboxylic acid cycle flux, decreased acyl carnitines, raised N-acetyl aspartate and improved sensorimotor behaviour compared with vehicle and untreated injured animals.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.