BML-111, a lipoxin receptor agonist, protects against acute injury via regulating the renin angiotensin-aldosterone system.

BML-111, a lipoxin receptor agonist, protects against acute injury via regulating the renin angiotensin-aldosterone system.

Model: Lipopolysaccharide-induced acute lung injury and lipopolysaccharide plus D-galactosamine induced acute liver injury

BML-111 protected against lipopolysaccharide-induced acute lung injury and lipopolysaccharide plus D-galactosamine induced acute liver injury, repressing angiotensin converting enzyme activity and increasing ACE2 activity, with all effects reversed by the lipoxin receptor inhibitor BOC-2.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.