Magnesium isoglycyrrhizinate alleviates liver injury in obese rats with acute necrotizing pancreatitis.
RatChemical/toxinSprague-Dawleyn = 36 rats randomly assigned to six groupsIntragastric30 mg/kgFor 7 days before pancreatitis was induced
Model: Acute necrotising pancreatitis induced by retrograde injection of 5 per cent sodium taurocholate into the biliary-pancreatic duct, in rats fed a high-fat diet or standard rat chow; animals killed 12 h after model induction
Obesity aggravated pancreatitis-induced liver injury, and magnesium isoglycyrrhizinate pre-treatment improved liver function and attenuated hepatic oxidative stress and inflammation in obese rats.
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.