Characteristic anti-inflammatory and antioxidative effects of enzymatic- and acidic- hydrolysed mycelium polysaccharides by Oudemansiella radicata on LPS-induced lung injury.
MouseEndotoxin/LPSMale400 mg/kg/d (dose reported for En-MPS)
Model: Lipopolysaccharide-induced acute lung injury
Both En-MPS and Ac-MPS lowered serum hs-CRP and complement C3, increased pulmonary SOD, GSH-Px, catalase and total antioxidant capacity, reduced myeloperoxidase activity and down-regulated malondialdehyde and lipid peroxide. TNF-alpha, IL-1beta and IL-6 in lavage fluid were significantly lower in m…
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.