Immunotherapy With Antiprogrammed Cell Death 1 Antibody Improves Outcome in a Mouse Model of Spinal Cord Injury Followed by Staphylococcus aureus Pneumonia.
MouseSpinal cord injuryUnspecifiedRjOrl:SWISS and BALB/cJIntraperitoneal injection
Model: Spinal cord injury induced immune depression syndrome followed by methicillin susceptible Staphylococcus aureus pneumonia
Blockade of PD-1 improved survival of spinal cord injured, infected mice and enhanced interferon gamma production by natural killer T cells as well as the number of viable CD4 T cells.
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