Stabilized collagen matrix dressing improves wound macrophage function and epithelialization.
MouseWoundC57BL/6MaleTopical wound dressing
Model: Murine excisional skin wound dressed with stabilised acellular equine pericardial collagen matrix, with parallel in vitro keratinocyte and bacterial adherence work
Excisional wounds dressed with sPCM showed complete closure at day 14 while control wounds remained open, with accelerated re-epithelialisation and improved healing quality through increased collagen deposition and maturation. Post-wound inflammation resolved rapidly with elevated IL-10, arginase-1…
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